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KMID : 0362319970220020801
Journal of Korean Academy of Operative Dentistry
1997 Volume.22 No. 2 p.801 ~ p.808
A STUDY ON THE INHIBITORY EFFECT OF ARECA CATECHU L. ON THE ACID PRODUCTION OF STREPTOCOCCUS MUTANS JC-2 AND ITS CYTOTXICITY


Abstract
In order to develop natural anticariogenic agents, we investigated inhibitory effects of
Areca catechu L. extracts on the acid production of Streptococcus mutans JC-2 and its
cytotoxicity on NIH 3T3 fibroblasts were also examined.
The results are as follows : 1.Major organic acid produced by Streptococcus mutans
JC-2 were lactic acid and acetic acid, and their productions were decreased by additions
of Area catechu L. extracts.
2. Area catechu L. extracts were showed noncytotoxicity on NIH 3T3 fibroblasts.
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